Table 1. Influence of oxaliplatin (L-OHP) on peripheral blood flow and preventive effect of goshajinkigan (GJG) in rats.

	day 3	day 10	4 weeks		8 weeks
			DW	GJG	DW	GJG
Head	108.3 ± 2.9	91.9 ± 4.5	89.9 ± 2.6*	87.9 ± 3.2	93.5 ± 3.8	93.1 ± 1.7
Right ear	101.5 ± 5.6	87.7 ± 2.0**	91.2 ± 3.4	91.8 ± 2.2	92.3 ± 4.1	91.4 ± 2.2
Left ear	104.8 ± 4.3	85.3 ± 2.2**	95.7 ± 2.9	95.0 ± 2.3	91.4 ± 3.2	91.5 ± 1.6
Right forelimb	100.8 ± 1.9	91.4 ± 3.1	89.0 ± 2.7**	101.7 ± 2.7##	100.3 ± 2.0	99.8 ± 1.9
Left forelimb	97.5 ± 3.1	93.1 ± 3.8	87.3 ± 2.8**	98.0 ± 3.3 #	97.2 ± 1.5	97.5 ± 1.5
Right hindlimb	114.2 ± 2.1	86.5 ± 6.9	88.3 ± 5.1	108.5 ± 4.4##	102.3 ± 4.4	104.8 ± 5.4
Left hindlimb	110.2 ± 0.9	85.8 ± 5.0	82.0 ± 4.5**	109.0 ± 4.5##	95.7 ± 4.7	98.9 ± 4.3
Tail	98.8 ± 2.5	90.9 ± 3.4	100.1 ± 2.2	99.2 ± 1.8	96.3 ± 3.3	105.8 ± 5.0

Mean ± S.E.M. (%); N = 7–8. *P < 0.05, **P < 0.01 vs naïve rats, ^#P < 0.05, ^##P < 0.01 vs L-OHP + DW.