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. 2015 Nov 6;5:16255. doi: 10.1038/srep16255

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After continuous treatment with 0.05 μM and 0.1 μM Pt-ctpy for one week and/or X-ray irradiation with doses ranging from 2 to 8 Gy, survival of GBM and NSCLC were determined using colony formation assay. Mean ± SE values of 3 independent experiments each performed in triplicate are shown. Survival (S) data after a radiation dose (D) were fit according to the linear-quadratic model. The linear parameter α and the quadratic parameter β are given for each experimental condition. Radiation-induced killing of Pt-ctpy treated cells was significantly enhanced in a concentration-dependent manner (ANOVA).