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. 2015 Nov 6;5:16237. doi: 10.1038/srep16237

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Copyright © 2015, Macmillan Publishers Limited

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(A) The effects of kenpaullone and mevastatin on Wnt/β-catenin signaling. Both compounds increase the amount of intact β-catenin. (B) The effects of kenpaullone and mevastatin on Mash1 expression. Kenpaullone increased Mash1 but not mevastatin. (C) The effects of kenpaullone, LY364947 and mevastatin on the Lmx1a expression. Increases of Lmx1a were detected for LY364947 and mevastatin. (D) The effect of LY364947 on Wnt signaling. LY364947 suppressed Sfrp1 and promoted Wnt1 expression. Full length blots are included in the Supplementary Information.