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. 2015 Nov 6;5:16257. doi: 10.1038/srep16257

Figure 2. CB1 receptor mediates 2-AG-induced suppression of the frequency of mEPSCs.

Figure 2

(a) Representative recording traces of mEPSCs under various treatments. Rimonabant (RIM, 1 μM) was added to cultures for two days. The treatment with TTX and 2-AG was the same as that described in Fig. 1. (b) Cumulative probability of mEPSC frequency recorded in neurons with different treatments (left) and mean percentage of changes in the frequency of mEPSCs in neurons with different treatments (right). (c) Cumulative probability of mEPSC amplitude recorded in neurons with different treatments (left) and mean percentage of changes in the amplitude of mEPSCs in neurons with different treatments (right). Data are mean ± SEM. *p < 0.05, ***p < 0.001, compared with the control; ##p < 0.01, ###p < 0.001, compared with 2-AG; §§p < 0.01, §§§p < 0.001, compared with RIM; ††p < 0.01, †††p < 0.001, compared with 2-AG + RIM (ANOVA with Dunn’s post hoc test).