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. 2015 Nov 6;5:16257. doi: 10.1038/srep16257

Figure 3. Chronic activity deprivation increases miniature spontaneous events and 2-AG fails to suppress them in cultured neurons lacking CB1R.

Figure 3

(a) Representative recording traces of mEPSCs under various treatments. (b) Cumulative probability of mEPSC frequency recorded in neurons with different treatments (left) and mean percentage of changes in the frequency of mEPSCs in neurons with different treatments (right). (c) Cumulative probability of mEPSC amplitude recorded in neurons with different treatments (left) and mean percentage of changes in the amplitude of mEPSCs in neurons with different treatments (right). Data are mean ± SEM. *p < 0.05, ***p < 0.001, compared with the control; ##p < 0.01, ###p < 0.001, compared with TTX; §p < 0.05, §§§p < 0.001, compared with TTX-2-AG (ANOVA with Dunn’s post hoc test).