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. 2015 Nov 6;5:16321. doi: 10.1038/srep16321

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Copyright © 2015, Macmillan Publishers Limited

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Molecular Characterization of hNSCs (a) Multi-Dimensional Scale analysis based on the mRNA transcription profiles of hiPSCs (blue), hNSCs (yellow) and hMLDCs (red). All profiled cell-types were generated from the same individual. (b) mRNA scatter blot of hiPSCs and hNSC; hNSC specific genes (red), hiPSC specific genes (green), genes observed in both cell types (black). (c) mRNA expression levels of OCT4, Nanog, Ki67, SOX2 and Nestin in hiPSC and hNSC quantified by RT-qPCR. (d) Gene Ontology analysis based on the 1428 genes specifically expressed in hNSCs when compared to hiPSCs and hMLDCs. (e) GO terms were subjected to a network analysis based on ReviGO (http://revigo.irb.hr/) and CytoScape (http://www.cytoscape.org/) softwares. The main GO sub-clusters are highlighted.