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. Author manuscript; available in PMC: 2016 Sep 23.
Published in final edited form as: Neuron. 2015 Sep 23;87(6):1181–1192. doi: 10.1016/j.neuron.2015.09.013

Figure 3. Sst+ and Pvalb+ Interneuron Activation Have Similar Effects on Response Bandwidths in Anesthetized Mice.

Figure 3

(A–C) FTPs for three representative units (A, B,and C) recorded in anesthetized mice without (black) and with (blue) activation of Sst+ interneurons. Data are represented as mean ± SEM. Dashed lines: bandwidths at half-height. Inset: unit’s mean waveform ± SD. Scale bar: 2 ms.

(D) Half-height bandwidths with versus without activation of Sst+ interneurons across the population of n = 76 units. Dark circles: units for which bandwidth change was significant (bootstrap test, n= 20 of 76 units). Light circles: units for which bandwidth change was not significant (n = 56 of 76 units).

(E–H) Corresponding to (A)–(D): representative units and group data showing the effect of Pvalb+ neuron activation (red) on FTP bandwidth in n = 63 units in anesthetized mice (n = 14 of 63 units significant).

(I) Box-and-whisker summary of the effects of Sst+ versus Pvalb+ interneuron activation on half-height bandwidths shows significant bandwidth reduction (sign-rank p < 0.001) that was not significantly different between groups (rank-sum p = 0.63).