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. 2015 Nov 6;5:16392. doi: 10.1038/srep16392

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(a) Microvessels were detected using CD31 immunofluorescence in primary tumor samples from OS patients. (b) Microvessels were detected in primary tumors from the LM8 xenograft model. Each bar represents the mean ± SD. Wild, wild type endostatin; p.104DN, heterozygous D104N polymorphism; p.104NN, homozygous of D104N polymorphism.