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. 2015 Nov 6;5:16204. doi: 10.1038/srep16204

Figure 1. Distribution of genetic risk score calculated from 11 SNPs of 11 AMD susceptibility genes.

Figure 1

We constructed a multi-locus genetic risk score by summing up the number of risk alleles of each single nucleotide polymorphism (SNP), weighted by its reported effect size (log odds ratio, OR). We evaluated both genetic risk score using effect size in Caucasian (A) and that using effect size in Asian (B). The effect sizes applied in this analysis are summarized in Supplementary Table 2. Pachychoroid neovasculopathy patients had significantly lower genetic risk scores for AMD than did neovascular AMD patients.