Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Sep 9;78(5):520–526. doi: 10.1038/pr.2015.145

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Official journal of the International Pediatric Research Foundation, Inc.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

PMC Copyright notice

Long-term effect of MSC treatment on sensorimotor behavior over time. Mice received either 0.5 × 10⁶ MSCs or vehicle intranasally at 10 d post-HI. Performance in the CRT was assessed at 10 d (i.e., before treatment) and 28 d and at 6 and 9 mo post-HI induction or sham operation. The results show that MSC administration improves performance in the CRT up to 9 mo post-HI. ^†P < 0.001; ^‡P < 0.001 (HI-MSC 28 d vs. HI-MSC 9 mo) with two-way ANOVA and Bonferroni post-hoc test. Animal numbers: 10-d sham, n = 16; HI-vehicle, n = 17; HI-MSC, n = 17; 28-d sham, n = 15; HI-vehicle, n = 17; HI-MSC, n = 17; 6-mo sham, n = 15; HI-vehicle, n = 17; HI-MSC, n = 14; 9-mo sham, n = 13; HI-vehicle, n = 16; HI-MSC, n = 13. HI, hypoxia–ischemia; MSC, mesenchymal stem cell.