Table 4.

Mean Baseline and 6 Month FACT-B Scores by Randomization Arm

	CF-WBI			HF-WBI			P*
	N	Mean	(95% CI)	N	Mean	(95% CI)
Baseline
Physical Well-Being	149	24.5	(23.9–25.1)	138	24.7	(24.1–25.4)	0.63
Functional Well-Being	148	22.2	(21.4–23.0)	138	22.5	(21.6–23.4)	0.63
Emotional Well-Being	148	20.4	(20.0–20.9)	138	20.5	(19.9–21.0)	0.92
Social Well-Being	149	24.4	(23.6–25.1)	138	25.1	(24.3–25.9)	0.16
FACT-G Total Score	148	91.6	(89.7–93.4)	138	92.8	(90.9–94.8)	0.35
Breast Cancer Concerns	149	27.2	(26.4–27.9)	138	27.3	(26.4–28.2)	0.86
FACT-B Total Score	148	118.8	(116.4–121.1)	138	120.1	(117.5–122.6)	0.46
Six months
Physical Well-Being	140	24.7	(24.1–25.3)	128	25.5	(24.9–26.1)	0.06
Functional Well-Being	140	23.2	(22.5–24.0)	128	24.1	(23.4–24.9)	0.10
Emotional Well-Being	140	21.1	(20.6–21.6)	128	21.3	(20.8–21.8)	0.60
Social Well-Being	140	24.6	(23.9–25.4)	128	24.8	(24.0–25.6)	0.74
FACT-G Total Score	138	93.6	(91.8–95.5)	128	95.7	(93.9–97.6)	0.12
Breast Cancer Concerns	141	28.6	(27.8–29.4)	128	28.7	(27.9–29.5)	0.82
FACT-B Total Score	138	122.3	(119.9–124.7)	128	124.5	(122.1–126.9)	0.20
Difference between 6 month and baseline outcomes
Physical well-being	140	0.28	(−0.40–0.95)	128	0.62	(0.04–1.19)	0.46
Functional Well-Being	139	1.01	(0.26–1.76)	128	1.5	(0.69–2.32)	0.38
Emotional Well-Being	139	0.67	(0.06–1.29)	128	0.93	(0.23–1.63)	0.58
Social Well-Being	140	0.23	(−0.35–0.81)	128	−0.31	(−1.24–0.61)	0.32
FACT-G Total Score	137	2.29	(0.58–4.00)	128	2.74	(0.91–4.56)	0.73
Breast Cancer Concerns	141	1.50	(0.71–2.28)	128	1.54	(0.62–2.46)	0.94
FACT-B Total Score	137	3.85	(1.74–5.96)	128	4.27	(2.01–6.53)	0.79

Abbreviations: CF (conventionally fractionated), HF (hypofractionated), WBI (whole breast irradiation)

^*P-value from t-test.