Fig. 1. HSV and VZV genomes. The HSV and VZV ORFs are represented by blue arrows on the genome maps. The diamond-shaped red lines denote the origin of DNA replication. Both the genomes have a unique long UL and a unique short US region flanked by repeat regions (RL and RS). The VZV genome is ∼30 kbp smaller than the HSV genome. The primary HSV-1 latency associated transcript (LAT) along with the two (nested) introns is shown.
