Table 3.
Analyses of discordant HPV typing results between the BMRT PCR assay and sequencing by comparing to the historical diagnoses and infection states of the cases
| Type | Numbers of BMRT negative/sequencing positive | Numbers of BMRT positive/sequencing negative | ||||
|---|---|---|---|---|---|---|
| Infection states | Historical diagnoses | Infection states | Historical diagnoses | |||
| Total | (Single + multiplea) | (N + CINI+ CINII-III + cancer) | Total | (Single + multiplea) | (N + CINI+ CINII-III + cancer) | |
| HPV16 | 3 | (2 + 1) | (3 + 0 + 0 + 0) | 7 | (0 + 7) | (7 + 0 + 0 + 0) |
| HPV18 | 4 | (0 + 4) | (1 + 2 + 1 + 0) | 1 | (0 + 1) | (1 + 0 + 0 + 0) |
| HPV31 | 1 | (1 + 0) | (0 + 0 + 1 + 0) | 1 | (0 + 1) | (1 + 0 + 0 + 0) |
| HPV59 | 0 | 3 | (1 + 2) | (2 + 0 + 1 + 0) | ||
| HPV53 | 0 | 3 | (0 + 3) | (0 + 3 + 0 + 0) | ||
| HPV33 | 3 | (1 + 2) | (3 + 0 + 0 + 0) | 1 | (0 + 1) | (1 + 0 + 0 + 0) |
| HPV58 | 4 | (0 + 4) | (4 + 0 + 0 + 0) | 1 | (0 + 1) | (1 + 0 + 0 + 0) |
| HPV56 | 0 | 9 | (1 + 8) | (7 + 0 + 1 + 1) | ||
| HPV52 | 2 | (1 + 1) | (2 + 0 + 0 + 0) | 5 | (1 + 4) | (3 + 0 + 1 + 1) |
| HPV35 | 0 | 3 | (0 + 3) | (0 + 0 + 2 + 1) | ||
| HPV68 | 0 | 1 | (1 + 0) | (1 + 0 + 0 + 0) | ||
| HPV51 | 0 | 2 | (0 + 2) | (1 + 0 + 1 + 0) | ||
| HPV39 | 0 | 1 | (0 + 1) | (1 + 0 + 0 + 0) | ||
| HPV26 | 0 | 1 | (0 + 1) | (1 + 0 + 0 + 0) | ||
| HPV6 | 1 | (0 + 1) | (1 + 0 + 0 + 0) | 3 | (0 + 3) | (1 + 1 + 1 + 0) |
| HPV11 | 0 | 8 | (1 + 7) | (3 + 1 + 4 + 0) | ||
| HPV81 | 2 | (1 + 1) | (2 + 0 + 0 + 0) | 6 | (0 + 6) | (6 + 0 + 0 + 0) |
| Total | 20 | (6 + 14) | (16 + 2 + 2 + 0) | 56 | (5 + 51) | (37 + 5 + 11 + 3) |
Note: N means normal in historical diagnosis. ashow the numbers of multiple infection cases, in which additional HPV types were detected by the indicated (Positive) method