Table 1.
Test drug | Model | Parameter significance |
---|---|---|
A. indica | Log (ρ/1 − ρ) = 0.434 + 0.384 × C − 0.0008 × C2 + 0.0001 × C3 | β0(0.0000) β1(0.0000) β2(0.0001) β3(0.0026) |
R. communis | Log (ρ/1 − ρ) = 0.225 + 0.324 × C − 0.0008 × C2 + 0.0008 × C3 | β0(0.0000) β1(0.0000) β2(0.0002) β3(0.0123) |
Az + Rc | Log (ρ/1 − ρ) = 0.125 + 0.454 × C − 0.0008 × C2 + 0.0011 × C3 | β0(0.0000) β1(0.0000) β2(0.0003) β3(0.0016) |
AMB | Log (ρ/1 − ρ) = 0.015 + 0.684 × C − 0.0008 × C2 + 0.0004 × C3 | β0(0.0000) β1(0.0000) β2(0.0004) β3(0.0021) |
Pentostam | Log (ρ/1 − ρ) = 0.012 + 0.724 × C − 0.0008 × C2 + 0.0014 × C3 | β0(0.0000) β1(0.0000) β2(0.0001) β3(0.0089) |
Az + Rc, combination of R. communis and A. indica; AMB, amphotericin B