Table 4.
Differential expression within gene ontologies of interest
| Identifier | Gene ontology | Acute | Chronic | ||||
|---|---|---|---|---|---|---|---|
| Genes | % Enriched | Genes | % Enriched | ||||
| AN (FC >1) | SD (FC <1) | AN (FC >1) | SD (FC <1) | ||||
| GO:0008219 | Cell death | 221 | 39 | 61 | 196 | 57 | 43 |
| Type of cell death | |||||||
| GO:0012501 | Programmed | 202 | 39 | 61 | 179 | 56 | 44 |
| GO:0070265 | Necrotic | 7 | 86 | 14 | 6 | 83 | 17 |
| GO:0010941 | Regulation of cell death | 181 | 39 | 61 | 151 | 58 | 42 |
| GO:0010942 | Positive regulation | 60 | 42 | 58 | 49 | 65 | 35 |
| GO:0060548 | Negative regulation | 100 | 38 | 62 | 86 | 53 | 47 |
| GO:0070997 | Neuron death | 47 | 21 | 79 | 37 | 41 | 59 |
| GO:1901216 | Positive regulation | 11 | 9 | 91 | 5 | 40 | 60 |
| GO:1901215 | Negative regulation | 28 | 21 | 79 | 26 | 42 | 58 |
| Voltage-gated potassium channel | |||||||
| GO:0005249 | Activity | 27 | 4 | 96 | 23 | 4 | 96 |
| GO:0008076 | Complex | 22 | 5 | 95 | 15 | 7 | 93 |
| GO:0045163 | Clustering | 1 | 0 | 100 | 0 | n/a | n/a |
FC fold change (AN FKPM divided by SD FKPM)