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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Neuropharmacology. 2015 Apr 20;97:376–382. doi: 10.1016/j.neuropharm.2015.04.009

Fig. 4.

Fig. 4

Fluorination plot of ACh at TrpB in 10:1 α6β2‡. Linear trend excludes 5-CNTrp and 4-F1Trp and has a slope of −0.10 which indicates the presence of a strong cation-π interaction between the indole side chain and the cationic agonist.