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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Neuropharmacology. 2015 Apr 20;97:376–382. doi: 10.1016/j.neuropharm.2015.04.009

Fig. 6.

Fig. 6

Fluorination plot of ACh, nicotine, and TC299423 at TrpB. The trendline is fit to ACh data only. The lack of a linear trend in nicotine and TC299423 indicates these agonists do not make cation-π interactions with the indole side chain.