Table 1.
Dose-response relationships for various mRNA α6:β2 injection ratios.
| Ratio | EC50 (uM) | nH | Imax | N |
|---|---|---|---|---|
| 50:1 | 0.097 ± 0.002 | 1.17 ± 0.03 | 8.25–57.3 | 11 |
| 20:1 | 0.139 ± 0.003 | 1.64 ± 0.05 | 0.25–1.44 | 15 |
| 10:1 | 0.119 ± 0.004 | 1.17 ± 0.04 | 4.85–70.7 | 16 |
| 5:1 | 0.094 ± 0.003 | 1.17 ± 0.04 | 0.70–79.9 | 18 |
| 2:1 | 0.109 ± 0.002 | 1.14 ± 0.03 | 0.94–79.5 | 11 |
| 1:1 | 0.15 ± 0.01 | 1.15 ± 0.06 | 4.42–14.2 | 10 |
| 1:2 | 0.125 ± 0.003 | 1.23 ± 0.05 | 3.06–31.7 | 11 |
| 1:5 | 0.35 ± 0.02 | 0.95 ± 0.04 | 0.70–8.21 | 13 |
| 1:10 | 0.80 ± 0.04 | 0.83 ± 0.02 | 1.01–4.67 | 16 |
| 1:20 | 0.52 ± 0.03 | 0.86 ± 0.03 | 1.01–10.9 | 11 |