Table 2.

Agonists at α6β2^‡.

	EC50 (µM)	nH	Imax (µA)	NEC50	Eff	NEff
ACh	0.169 ± 0.003	1.36 ± 0.03	0.28–14.9	12	–	–
Nic	0.057 ± 0.002	1.38 ± 0.05	9.48–54.4	10	0.49 ± 0.03	22
metaNic	0.74 ± 0.02	0.98 ± 0.03	0.43–40.4	13	0.64 ± 0.04	15
Var	0.031 ± 0.003	1.08 ± 0.08	0.51–12.1	15	0.33 ± 0.02	19
Cyt	0.027 ± 0.001	1.31 ± 0.05	0.57–31.9	11	0.28 ± 0.01	20
Ch	159 ± 7	1.32 ± 0.05	2.08–15.4	14	0.33 ± 0.02	15
CCh	1.36 ± 0.05	1.12 ± 0.04	3.63–52.5	13	0.87 ± 0.04	18
Epi	0.00035 ± 0.00003	1.9 ± 0.2	0.47–2.81	12	0.54 ± 0.02	19
TC299	0.071 ± 0.003	0.99 ± 0.04	1.73–21.9	12	0.59 ± 0.04	16