Table 1.

Study populations included in the pooled analysis

Study	Study design	Platform	Control (n)	SCC (n)	AC (n)	SCLC (n)
Discovery set
NCI/EAGLE	Population based	HumanHap 550K	5735	1447	1844	706
Han Chinese	Hospital based		3077	825	1307	179
IARCa	Hospital/population based	HumanHap 317Kb	3791	1031	595	451
ICR	Hospital-based cases, 1958 birth controls	HumanHap 550K	2699	611	465	530
MD Anderson	Hospital based	HumanHap 317Kb	1137	302	558	—
Harvard	Hospital based	HumanHap 610K	970	215	486	—
deCODE	Nested case–control	HumanHap 317Kb	11227	179	346	98
Japan Aichi	Population based	HumanHap 550K	942	118	412	64
Germany	Population based	HumanHap 550K	484	100	198	109
Liverpool	Population-based cases, WTCCII controls	HumanHap 317K	2501	167	169	57
Mayo	Hospital based	HumanHap 370K/610K	377	16	221	10c
Toronto	Hospital and population based	HumanHap 317Kd	464	50	90	22
MSKCC	Hospital based	HumanHap 317K	52	5c	63	1c
Total			33456	5061	6756	2216
Validation set
EPIC Lung	Nested case–control	Axiom custom array	1003	218	297	148
LLP	Hospital based	Axiom custom array	336	148	137	49
NHS	Nested case–control	Axiom custom array	324	0	195	43
PHS	Nested case–control	Axiom custom array	169	23	67	21
MEC	Nested case–control	Axiom custom array	213	26	79	25
MSH-PMH	Clinic based	Axiom custom array	921	210	641	83
Total			2966	625	1417	369

^aIARC study consists of cases and controls from CARET, Central Europe, HUNT\Tromso, Estonia and France studies.

^bUsed imputed data to get a set of SNPs closer to the 550K chip where measure of imputation quality was above 0.3 from MACH.

^cNot included in the combined estimates.

^dUsed imputed data to get a set of SNPs closer to the 550K chip where measure of imputation quality was above 0.3 from Impute.