Table 2.
Multivariate Hazard Cox regression survival analysis
| HR (+95% CI) | p-values | |
|---|---|---|
| MPOlow/CD8low vs. all other combinations | 0.35 + 0.34 | 0.002 |
| Age | 1.03 + 0.005 | <0.0001 |
| Gender | 0.68 + 0.09 | <0.0001 |
| pT stage | 1.81 + 0.08 | <0.0001 |
| Tumor grade | 1.27 + 0.13 | 0.056 |
| pN stage | 1.91 + 0.06 | <0.0001 |
| Vascular invasion | 1.46 + 0.11 | 0.0004 |
| Tumor border configuration | 1.46 + 0.12 | 0.0016 |
| Microsatellite stability (deficient vs. proficient) | 1.80 + 0.15 | <0.0001 |
Multivariate analyses showing Hazard Ratios and p-value for all CRC (n = 1062 less than 1420 due to missing values) conferred by CD8+ and MPO density, age, sex, tumor size, tumor grade, vascular invasion, tumor border configuration, and microsatellite stability.