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. 2015 Jun 17;11(10):2425–2433. doi: 10.1080/21645515.2015.1055429

Table 3.

Adverse events in the safety analysis population

Event Treatment vaccine N = 830 Control vaccine N = 830 p value
Serious adverse events(no. of participants)      
 Events within 7 d after injection 1(0.12%) 0(0%) 1.0000
 Events from day 8 to day 30 2 (0.24%) 2 (0.24%) 1.0000
Solicited adverse reactions within 7 d after an injection(no. of participants)      
  Any 285(34.34%) 296(35.66%) 0.6069
  Grade 3 20(2.41%) 19(2.29%) 1.0000
 Injection-site reactions      
 Pain      
  Any 201(24.22%) 202(24.34%) 1.0000
  Grade 3 0(0.00%) 0(0.00%) 1.0000
 Redness      
  Any 50(6.02%) 62(7.47%) 0.2817
  Grade 3 10(1.20%) 12(1.45%) 0.9320
 Swelling      
  Any 44(5.30%) 53(6.39%) 0.4026
  Grade 3 10(1.20%) 13(1.57%) 0.8360
 Pruritus      
  Any 20(2.41%) 15(1.81%) 0.4949
  Grade 3 0(0.00%) 0(0.00%) 1.0000
 Induration      
  Any 1(0.12%) 0(0.00%) 1.0000
  Grade 3 0(0.00%) 0(0.00%) 1.0000
 Systemic reactions      
 Fever      
  Any 82(9.88%) 88(10.60%) 0.6282
  Grade 3 3(0.36%) 1(0.12%) 0.3549
 Headache      
  Any 24(2.89%) 32(3.98%) 0.2808
  Grade 3 0(0.00%) 0(0.00%) 1.0000
 Fatigue      
  Any 30(3.61%) 30(3.61%) 1.0000
  Grade 3 0(0.00%) 0(0.00%) 1.0000
 Nausea or vomiting      
  Any 6(0.72%) 12(1.45%) 0.2353
  Grade 3 0(0.00%) 0(0.00%) 1.0000
 Diarrhea      
  Any 9(1.08%) 10(1.20%) 1.0000
  Grade 3 1(0.12%) 1(0.12%) 1.0000
 Rash      
  Any 5(0.60%) 7(0.84%) 0.7736
  Grade 3 0(0.00%) 0(0.00%) 1.0000
 Allergy      
  Any 2(0.24%) 1(0.12%) 1.0000
  Grade 3 1(0.12%) 0(0.00%) 1.0000