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. 2015 Jun 19;11(8):1972–1982. doi: 10.1080/21645515.2015.1022008

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© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 4. — Comparison of host responses to DNA vaccination. (A) Hemagglutination inhibition (HI) antibody titers from the challenge groups of mice (n = 10/group) 3 weeks after the final immunization and prior to viral challenge. (B) The number of IFN-γ secreting splenocytes 3 weeks after the final vaccination. Splenocytes were stimulated with H1HA pooled peptides and IFN-γ secretion was reported as spot forming units (SFU) per million splenocytes. Group mean ± SEM are reported. ***, P < 0.0005 for DNA HI antibody titers compared to naive.