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. 2015 Jun 19;11(8):1972–1982. doi: 10.1080/21645515.2015.1022008

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© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 6. — Protection from H1N1 A/Puerto Rico/8/34 virus challenge in DNA immunized mice. Percentage body weight loss following lethal viral challenge with 50 LD₅₀ PR8 Cambridge virus and Kaplan-Meier survival curve showing percentage survival of mice from each group. (A and B) Percentage body weight loss and survival for dbDNA™ PR8 immunized mice. (C and D) Percentage body weight loss and survival for pDNA PR8 immunized mice. Group mean and SEM are reported. ###, P < 0.0005 for dbDNA™ PR8 body weight (%) compared to naïve. ***, P < 0.0005 for pDNA PR8 body weight (%) compared to naïve.