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. 2015 Nov 6;6:536. doi: 10.3389/fimmu.2015.00536

Figure 2.

Figure 2

(A) Comparison of TCMR01 and TCMR02 with the normal and nephrectomy controls. Unsupervised hierarchal clustering of TCMR01, TCMR02, NEPH01 (nephrectomy) and NORM01 (normal biopsy samples). (B) The subtypes of T cell-mediated rejection (TCMR) classified by unsupervised hierarchical clustering. After filtering the initial 54,675 Affymetrix probe sets based upon scaled expression and coefficient of variation, we identified two distinct groups of T cell-Mediated Rejection: TCMR01 (left) and TCMR02 (right). The two sub-diagnoses were differentiated by 1933 significant genes based upon false-discovery rate corrected p-values of 0.05.