Table 1. Characteristics of the children and adolescents with severe therapy-resistant asthma.^a .

Variables	Patients
	(N = 21)
Male gender, n (%)	10 (47.6)
Age, years	9.20 2.98
Family history of asthma	21 (100.0)
Household smoking	8 (38.0)
Allergic rhinitis	21 (100.0)
Atopic dermatitis	4 (19.0)
Obesity	5 (23.8)
Age at symptom onset, years	1.14 0.95
GERD symptoms	3 (14.3)
Continuous oral corticosteroid use	5 (23.8)
Montelukast use	6 (25.6)
History of hospitalization	11 (52.4)
Serum IgE, IU/mLb
< 30	0 (0.0)
30-500	7 (36.8)
> 500	12 (63.2)
Bronchodilator response	6 (25.6)
Abnormal pH monitoring resultsc	6 (60.0)

GERD: gastroesophageal reflux disease. ^aValues expressed as n (%) or mean SD. ^bn = 19. ^cn = 10.