Table 3. Toxicity of stereotactic body radiation therapy for central lesions, in absolute numbers of patients.
Study | Deaths | Grade 3 toxicitya | |
---|---|---|---|
Acute | Late | ||
Haasbeek et al.36 | cardiac death: 1; respiratory failure: 1 | 1 | 4 |
Nuyttens et al.37 | - | 4 | 6 |
Rowe et al.38 | bronchial necrosis: 1 | 4 | |
Oshiro et al.39 | hemoptysis: 1 | 0 | 2 |
Unger et al.40 | bronchial fistula: 1 | 1 | 0 |
Milano et al.41 | bronchial/tracheal lesion: 4 | 0 | 1 |
Chang et al.42 | - | 1 |
Chest wall pain, dyspnea, rib fracture, pneumonitis, or chronic cough.