Figure 1.
The 10 most abundantly expressed miRs in the RV of sham and PS animals were compared with the 10 most abundant miRs in the LV of sham and SRF-induced hypertrophy. Data are expressed as median signal intensity. LV data were obtained from GEO datasets. MicroRNA (miR) distribution is similar in both the RV and LV with miR-1, 133, and let-7 family being the most abundant. RV-right ventricle, LV-left ventricle, RVH-right ventricular hypertrophy, LVH-left ventricular hypertrophy. Reproduced from Sushma Reddy, Mingming Zhao, Dong-Qing Hu, Giovanni Fajardo, Shijun Hu, Zhumur Ghosh, Viswanathan Rajagopalan, Joseph C. Wu, Daniel Bernstein, Dynamic microRNA expression during the transition from right ventricular hypertrophy to failure. Physiological Genomics 2012;44:562–575.