Fig. 4.
Determination of killing rate profile for different classical anti-malarial drugs. Plasmodium falciparum viability time-course profile for artesunate, chloroquine, atovaquone, and pyrimethamine at 10 × IC50. Fast-acting anti-malarial drugs (artesunate and chloroquine) can be readily distinguished from moderate or slow-acting compounds (pyrimethamine and atovaquone). The number of viable infected erythrocytes was normalized using the number of untreated parasites. Error bars represent SEM for 4–9 replicates