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. 2015 Nov 5;11:36. doi: 10.1186/s12993-015-0080-x

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© Aarsland et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The kynurenine pathway of tryptophan catabolism. INF-γ interferon gamma, TDO tryptophan 2,3-dioxygenase, IDO indole 2,3-dioxygenase, KYNU kynureninase, KAT kynurenine aminotransferase, KMO Kynurenine mono-oxygenase, PLP pyridoxal 5′-phosphate (vitamin B6), FAD flavin adenine dinucleotide (vitamin B2), NAD nicotinamide adenine dinucleotide