TABLE I.
Transmission Counts for Alleles in Each of Three CAG Repeat Rang
| Range II 27–35 CAG repeats |
Range III 36–39 CAG repeats |
Range IV ≥40 CAG repeats |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Total | Male | Female | Total | Male | Female | Total | Male | Female | |
| Transmissions | 69 | 32 | 37 | 44 | 15 | 29 | 534 | 221 | 313 |
| No change | 65 | 31 | 34 | 26 | 9 | 17 | 122 | 33 | 89 |
| Expansions | 1 | 1 | 0 | 17 | 6 | 11 | 264 | 145 | 118 |
| Contractions | 3 | 0 | 3 | 1 | 0 | 1 | 148 | 42 | 106 |
| Expansions into other ranges | 0 | 0 | 0 | 6 | 3 | 3 | Not applicable | Not applicable | Not applicable |
| Contractions into other ranges | 0 | 0 | 0 | 0 | 0 | 0 | 12 | 2 | 10 |
| Mean change | −0.17 | 0.06 | −0.38 | 0.91 | 1.87 | 0.41 | 1.33 | 3.22 | −0.01 |
Range I (26 CAGs or fewer) was omitted for clarity as there were no changes into any penetrant range. Table represents the total number of transmissions; transmissions of alleles with and without changes in repeat length; the mean change of the repeat length; and the number of expansions and contractions into other ranges. Statistics are broken down by sex. Bold text highlights totals in each range.