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. Author manuscript; available in PMC: 2015 Nov 6.
Published in final edited form as: Nature. 2013 Feb 28;494(7438):492–496. doi: 10.1038/nature11935

Figure 4. Nucleoside supplementation reduces segregation error frequency and prometaphase DNA damage.

Figure 4

a) % Anaphases with segregation errors ± 48 h nucleoside supplementation 24 h after siRNA transfection as indicated (mean±s.e.m, 3 experiments, Two-tailed t-test, **p<0.01). b) % Anaphases with segregation errors ± 48 h nucleoside supplementation in CIN+ cell lines as indicated (mean±s.e.m, 3 experiments, Two-tailed t-test, **p<0.01). c) Fold change in % prometaphases exhibiting ≥3 γH2AX foci ± 48 h nucleoside supplementation in CIN+ cell lines as indicated (n≥100 cells per condition per cell line, mean±s.e.m of 3 experiments). Un-normalised data is shown in Supplementary 13a.