Table 1.

Combination index of different concentrations of PP242 and CTX

Concentration of PP242 (nM)	Concentration of CTX (μg/mL)	Effect (Caco-2)	Effect (HT-29)	CI (Caco-2)	CI (HT-29)
50.0	0.01	0.15	0.08	1.54	1.80
100.0	0.1	0.44	0.28	1.37	0.47
300.0	1.0	0.60	0.43	0.30	0.76
600.0	10.0	0.75	0.61	0.38	0.85
1,000.0	20.0	0.77	0.69	0.48	0.87

Abbreviations: CI, combination index; CTX, cetuximab.