Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov 2;8:257–267. doi: 10.2147/TACG.S90215

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Pandey et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Linkage disequilibrium (LD) and forest plots of ROCK2 and MYLK.

Notes: (A) 88 kb ROCK2 block and (B) 7 kb MYLK block. SNPs were arranged according to the chromosome position. Gabriel et al’s39 confidence interval algorithm was chosen to build the blocks. The values in the boxes represent the D′ values. Standard (D′/LOD) color scheme was kept for the LD plot. (C) ROCK2-protective haplotype GGGTTGGT. (D) MYLK-risk haplotype CTA and (E) MYLK-protective haplotype GCG. The order of alleles in the forest plots is as follows: for ROCK2, rs978906, rs2290156, rs10495582, rs10167277, rs10929727, rs6716817, rs4477886, and rs10929728, and for MYLK, rs11717814, rs40305, and rs820336. ^*P<0.05.

Abbreviations: HAPE, high altitude pulmonary edema; HAPE-c, HAPE controls; HAPE-p, HAPE patients; HLs, highlanders; LOD, logarithm of the odds; SNPs, single-nucleotide polymorphisms.