Figure 3. . Size and zeta potential analysis of oxime ether lipid liposomes with or without addition of Dicer substrate of RNA.

Liposomes (10 µM) alone and in complexation with DS RNA (50 nM) were analyzed for their average diameter and zeta potential as described in the Methods section. (A) Diameter (nm) for various lipids (black bars) or in complexation with DS RNA (crossed bars). (B) Zeta potential analyses of oxime-ether lipids liposomes alone (black bars) and in complexation with DS RNA (crossed bars) are expressed in mV. The error bars in (A & B) represent standard deviation (n = 3).

DS RNA: Dicer substrate of RNA.