Fig 6. Systemic inflammation in ATMIN^ΔLNBS1^ΔL mice is T cell intrinsic.

(A) Model for the reconstitution of RAG^-/- mice reconstituted with intravenously injected with CD3⁺ TCRβ⁺ sorted splenic T cells from control or ATMIN^ΔLNBS1^ΔL mice. (B) Kaplan-Meier survival curve of RAG^-/- mice that were reconstituted as in A. Survival was monitored for 24 weeks post reconstitution. (C) Representative flow cytometry plots of TCRβ⁺ T cells as well as CD4⁺ and CD8⁺ T cells (gated on the TCRβ⁺ population) and Gr1⁺CD11⁺ neutrophils in the spleen of RAG^-/- mice injected with control or ATMIN^ΔLNBS1^ΔL T cells. **P<0.01.