Table 2.

Risk Adjusted Event Rates of Surgical Site Infection, by Agent

	Observed incidence SSI, % [95% CI]	Expected incidence SSI, % [95% CI]	RAER [95% CI]	p Value
Skin antiseptic agent
CHG	4.0 [3.1–5.0]	4.7 [4.2–5.1]	0.85 [0.78–1.10]	0.28
CHG+IPA	4.5 [4.0–5.2]	4.1 [3.8–4.5]	1.10 [1.00–1.21]	0.06
PVI	6.0 [4.3–8.0]	6.1 [5.2–7.0]	0.98 [0.85–1.15]	0.96
IPC+IPA	5.3 [3.3–7.9]	5.7 [4.7–6.7]	0.93 [0.79–1.12]	0.51
Sub group IPA vs non-IPA
Non-IPA	4.5 [3.7–5.4]	5.0 [4.6–5.4]	0.91 [0.76–1.09]	0.39
IPA	4.6 [4.0–5.2]	4.2 [3.9–4.6]	1.10 [1.00–1.19]	0.07

CHG, chlorhexidine; CHG+IPA, chlorhexidine in isopropyl alcohol; PVI, povidone-iodine; IPC+IPA, povacrylex-iodine in isopropyl alcohol; IPA, isopropyl alcohol; RAER, risk adjusted event rates; SSI, surgical site infection.