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. Author manuscript; available in PMC: 2015 Nov 6.
Published in final edited form as: J Am Coll Surg. 2013 Nov 27;218(3):336–344. doi: 10.1016/j.jamcollsurg.2013.11.018

Table 4.

Risk-Adjusted Event Rates of Surgical Site Infection in Elective Colorectal Cases, by Agent

Observed incidence SSI, % [95% CI] Expected incidence SSI, % [95% CI] RAER, [95% CI] p Value
Skin preparation agent
 CHG 4.4 [3.1–6.0] 4.9 [4.3–5.5] 0.90 [0.63–1.22] 0.48
 CHG+IPA 5.5 [4.5–6.7] 5.3 [4.8–5.8] 1.04 [0.85–1.26] 0.67
 PVI 5.2 [3.4–7.7] 5.0 [4.0–6.0] 1.04 [0.68–1.54] 0.85
 IPC+IPA 4.9 [2.7–8.1] 4.9 [3.8–6.0] 1.00 [0.55–1.65] 0.99
Sub group IPA vs non-IPA
 Non-IPA 4.7 [3.6–6.0] 5.0 [4.5–5.5] 0.94 [0.72–1.19] 0.65
 IPA 5.4 [4.5–6.5] 5.2 [4.8–5.7] 1.04 [0.87–1.25] 0.69

CHG, chlorhexidine; CHG+IPA, chlorhexidine in isopropyl alcohol; PVI, povidone-iodine; IPC+IPA, povacrylx-iodine in isopropyl alcohol; IPA, isopropyl alcohol; RAER, risk adjusted event rates; SSI, surgical site infection.