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. 2015 Nov 6;10(11):e0142347. doi: 10.1371/journal.pone.0142347

Fig 3. Effect of adrenergic antagonists on epinephrine-induced uptake of I-PGUS across the BBB.

Fig 3

Upper panel shows that more general alpha, alpha1, and alpha2 antagonists but not beta antagonists blocked epinephrine’s effect. Lower panel shows results that the highly selective alpha1 adrenergic receptor antagonist benoxathian but not the highly selective beta adrenergic receptor antagonist CPG20712A blocked the effect of epinephrine. **p<0.01 and ***p<0.001 inc comparison to control; ##p<0.01 and ###p<0.001 in comparison to epinephrine.