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. 2015 Nov 6;10(11):e0142347. doi: 10.1371/journal.pone.0142347

Fig 5. Combined effect of alpha1 (cirazoline) and alpha2 (clonidine) adrenergic receptor agonists on I-PGUS transport across the BBB.

Fig 5

Neither drug alone affected I-PGUS uptake, but combined they effectively increased transport across the BBB. ***p<0.001 in comparison to control; n = 12/group.