Table 4. Multiple linear regression analysis of relationships between S100A11 expression and clinicopathologic characteristics of stage I lung adenocarcinomas.
| Subjects | Coefficient B | Standard Error | Standardized Coefficient β | P-value |
|---|---|---|---|---|
| Age | ||||
| <65 | 1 | |||
| > = 65 | 2.069 | 9.944 | 0.016 | 0.835 |
| Gender | ||||
| Male | 1 | |||
| Female | 2.878 | 9.612 | 0.023 | 0.765 |
| Histologic Grade | ||||
| WEL | 1 | |||
| MOD | 19.767 | 12.240 | 0.156 | 0.108 |
| POR | 31.061 | 14.925 | 0.216 | 0.039 |
| Lymphatic or vascular involvement | ||||
| Absent | 1 | |||
| Present | 13.261 | 11.532 | 0.094 | 0.252 |
WEL, well differentiated; MOD, moderately differentiated; POR, poorly differentiated carcinomas.
Histologic subtypes were excluded from factors due to the strong correlation that existed with histologic grade (Spearman’s coefficient 0.567, P<0.001).