Fig 4. siRNA-mediated knock-down of LRP/LR in HEK293 and MDA_MB231 cells.
The expression level in HEK293 and MDA_MB231 cells was investigated 72h post-transfection with siRNA-LAMR1. Densitometric analysis of western blot signals revealed a significant (*** p < 0.001) 90.48% and 92.59% reduction in LRP protein expression in A) HEK293 and B) MDA_MB231 cells, respectively, compared to control non-transfected cells (set at 100%).