Table 1. Ever Smoker Patient data.

Sample	Site a	Sex	Age	Tobacco/Betel b	Ethanol c	Path. Stage	Grade d	Immune State
OSCC110	T	M	50	Bet+Tob	None	T2N0M0	Well Diff	Norm
OSCC129	LG	M	52	F-Tob	L/M	T1N0M0	Well Diff	Norm
OSCC329	LG	M	59	F-Tob	None	T4aN0M0	Poorly Diff	Norm
OSCC359	T	M	61	Tob	Heavy	T4N2cM0	Mod Diff	Norm
OSCC416	T	M	61	Tob	L/M	TcisN0M0	N/A	Norm
OSCC449	LG	F	62	Tob	None	T4NoM0	Mod Diff	Norm
OSCC466	T	M	64	Tob	Heavy	T2N0M0	Poorly Diff	HIV positive
OSCC485	FOM	M	56	Tob	None	T4aN2bM0	Mod Diff	Norm
Sample	Site	Sex	Age	Tobacco/Betel	Ethanol	Path. Finding		Immune State
BL117	LM	F	46	Tob	L/M	Canicular Adenoma		Norm
BL129	Bu	M	27	Tob	None	Ameloblastoma		Norm
BL149	LG	F	54	F-Tob	None	Hyperkeratosis		Norm
BL319	T	F	33	Tob	L/M	Granular Cell Tumor		Norm
BL367	Bu	M	44	ST	None	Hyperkeratosis, Mucositis		Norm
BL474	LG	F	77	F-Tob	L/M	Fibrous hyperplasia		Norm
BL482	T	M	58	Tob	L/M	Hyperkeratosis		Norm
BL490	UG	M	51	Tob	L/M	Fibrous Hyperplasia		Norm
BL495	UG	M	60	Tob	None	Hyperkeratosis		Norm

^aT, tongue; LG/UG lower/upper gingiva; FOM, floor of mouth; Bu, buccal mucosa, LM, lip mucosa.

^bTob, Tobacco user; if former user than F-Tob.; Bet, betel use; ST, smokeless tobacco user

^c L/M, light to moderate intake of ethanol up to 50 grams per day, Heavy, intake of ethanol > 50 g/day.

^d well differentiated, Well Diff; moderately differentiated, Mod Diff; Poorly differentiated, Poorly Diff