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. 2015 Nov 6;10(11):e0142250. doi: 10.1371/journal.pone.0142250

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© 2015 Chantreau et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 6 — Typical measurements of the constitutive activity of the L2.58P (a), L2.59P (b), I2.60P (c) and A5.50P (d) TSHRs. In each panel, the cAMP accumulation obtained in the presence of the mutated and WT TSHR is indicated by open and closed symbols, respectively.