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. 2015 Nov 6;10(11):e0142062. doi: 10.1371/journal.pone.0142062

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© 2015 Hirano, Kanno

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 1 — (A) The cells were grown in glass-bottom culture dishes in F12 complete medium and observed using confocal microscopy. Fluorescence images were recorded at 1-min intervals. The arrows and arrowheads indicate the formation and fate of two separate macropinocytic sites. See also S1 Movie. (B) Scanning electron micrographs of GFP-MARCO-CHO cells. The right panel provides a higher magnification image of the boxed area indicated in the left panel. The arrow indicates the macropinocytic structure.