Table 2. IPA analysis.
A summary of Ingenuity Pathway Analysis (IPA) showed the top networks and top predicted canonical pathways affected by the altered expression of genes in response to the treatment of the leaf extract in HepG2 cells.
| ID | Top networks | Scorea |
|---|---|---|
| 1 | Lipid metabolism, small molecule biochemistry, hematological disease | 36 |
| 2 | Ophthalmic Disease, Connective Tissue Disorders, Inflammatory Disease | 35 |
| 3 | Digestive System Development and Function, Organ Morphology, Developmental Disorder | 32 |
| 4 | Carbohydrate Metabolism, Small Molecule Biochemistry, Free Radical Scavenging | 24 |
| 5 | Hereditary Disorder, Neurological Disease, Organismal Injury and Abnormalities | 24 |
Notes.
a
A score of 2 or higher indicates at least 99% confidence of not being generated by random chance and higher scores indicate a greater confidence.