Table 1. Central genes in the PPI network.

The top 15% genes with the highest degrees, betweenness centrality, and closeness centrality scores in the enriched PPI network are shown.

Genes	Degree	Genes	Betweenness centrality	Genes	Closeness centrality
VEGFA	23	IL6	0.253	CHL1	0.667
JUN	20	JUN	0.205	FAF1	0.667
ITGB1	17	HRAS	0.153	MGAT4B	0.667
IL6	17	EZR	0.122	MGAT4A	0.667
MYC	17	MYC	0.12	JUN	0.408
IL2	13	VEGFA	0.111	MYC	0.388
BMP4	13	VIM	0.109	IL6	0.384
CSF2	12	CALM1	0.107	VEGFA	0.38
ITGA6	12	BMP4	0.074	HRAS	0.366
HRAS	11	ITGA6	0.069	ITGA6	0.36
KDR	11	CYP2C8	0.063	ITGB1	0.359
BMPR2	11	PLA2G2D	0.061	IL2	0.357
EZR	11	PLA2G2A	0.061	VIM	0.354
CALM1	11	FLNA	0.058	CSF2	0.349
FLNA	10	PLCE1	0.054	ITGA2	0.341
ITGA2	10	TUBB4A	0.051	NGF	0.337
BMPR1A	10	THBS1	0.051	TUBB4A	0.332
FGF1	9	ITGB1	0.049	EZR	0.329
BMP2	9	IL2	0.049	FLNA	0.329
FASLG	9	CSF2	0.048	FASLG	0.329
TNNT2	9	ADORA2B	0.048	CALM1	0.326