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Effect of short-term alcohol exposure for 6 days on prostaglandin-E2 (PGE2) release in vitro from the MBH of prepubertal rats. The content of PGE2 released into the medium was determined by ELISA. Note that alcohol-treated animals showed a marked decrease in the basal PGE2 release compared with control animals. The respective bars illustrate the mean (± SEM) of an N of 14 for control and an N of 9 for alcohol. **p < 0.01 vs. control. Modified from Srivastava et al., 2011.
