Table 2.
Clinicopathological correlations with positive lymph node ratio (LNR)
| Characteristics | N0 (LNR = 0) (%) |
a (%) |
LNR > 0.19 (%) |
P value |
|---|---|---|---|---|
| Gender | 0.11 | |||
| Female | 90 (51.1) | 68 (38.6) | 18 (10.3) | |
| Male | 93 (41.9) | 94 (42.3) | 35 (15.8) | |
| Age, years (Mean ± SD) | 65.2 ± 9.3 | 62.0 ± 9.8 | 62.0 ± 8.9 | 0.004 |
| Number of lymph nodes examined (Mean ± SD) | 23.1 ± 8.1 | 25.9 ± 10.4 | 24.5 ± 10.5 | 0.024 |
| Tumor differentiation | 0.24 | |||
| Well-Moderate | 118 (46.8) | 96 (38.1) | 38 (15.1) | |
| Poor | 65 (44.5) | 66 (45.2) | 15 (10.3) | |
| Pathologic tumor stage | <0.001 | |||
| ypT0, ypT1, ypT2 | 35 (83.3) | 7 (16.7) | 0 (0) | |
| ypT3 | 148 (41.6) | 155 (43.5) | 53 (14.9) | |
| Resection margin | 0.02 | |||
| Negative | 173 (47.1) | 150 (40.9) | 44 (12.0) | |
| Positive | 10 (32.3) | 12 (38.7) | 9 (29.0) | |
| AJCC stage | <0.001 | |||
| IA and IB | 35 (100) | 0 | 0 | |
| IIA | 148 (100) | 0 | 0 | |
| IIB | 0 | 162 (75.3) | 53 (24.7) | |
| HTRGb | <0.001 | |||
| CAP grade 0/1 | 43 (68.3) | 17 (27.0) | 3 (4.7) | |
| CAP grade 2/3 | 140 (41.8) | 145 (43.3) | 50 (14.9) | |
| Recurrencec | <0.001 | |||
| None | 79 (63.7) | 39 (31.5) | 6 (4.8) | |
| Local | 35 (42.2) | 31 (37.3) | 17 (20.5) | |
| Distant | 69 (37.1) | 87 (46.8) | 30 (16.1) |
a
0.19 represents the 75th percentile value of lymph node ratio (LNR)
b
HTRG, histopathologic tumor response grade
c
Recurrence data was not available for 5 patients