Table 4.
Risk ratios and 95 % confidence intervals for the association between educational level and having outcome measures of rheumatoid arthritis decrease over the median, or achieve remission
| Visits | University/college degree | Outcome values decrease over the median or achieve remission | |||
|---|---|---|---|---|---|
| No | Yes | Risk ratio crude (95 % CI) | Risk ratio* (95 % CI) | ||
| DAS28 low disease activity | |||||
| 3 months | No | 960 (76.4) | 297 (23.6) | 1.0 ref. | 1.0 ref. |
| Yes | 789 (74.8) | 266 (25.2) | 1.05 (0.95 to 1.16) | 1.00 (0.91 to 1.11) | |
| 6 months | No | 737 (78.2) | 206 (21.8) | 1.0 ref. | 1.0 ref. |
| Yes | 801 (77.3) | 235 (22.7) | 1.02 (0.93 to 1.13) | 0.98 (0.88 to 1.09) | |
| 1 year | No | 822 (78.2) | 229 (21.8) | 1.0 ref. | 1.0 ref. |
| Yes | 1160 (75.4) | 379 (24.6) | 1.07 (0.99 to 1.14) | 1.04 (0.97 to 1.13) | |
| DAS28 good response | |||||
| 3 months | No | 1073 (75.9) | 340 (24.1) | 1.0 ref. | 1.0 ref. |
| Yes | 642 (75.3) | 211 (24.7) | 1.02 (0.91 to 1.16) | 0.98 (0.86 to 1.11) | |
| 6 months | No | 829 (78.1) | 233 (21.9) | 1.0 ref. | 1.0 ref. |
| Yes | 682 (77.8) | 195 (22.2) | 1.01 (0.90 to 1.14) | 0.96 (0.85 to 1.08) | |
| 1 year | No | 964 (78.5) | 264 (21.5) | 1.0 ref. | 1.0 ref. |
| Yes | 960 (75.0) | 320 (25.0) | 1.10 (1.01 to 1.20) | 1.07 (0.98 to 1.17) | |
| DAS28 remission | |||||
| 3 months | No | 1214 (76.6) | 371 (23.4) | 1.0 ref. | 1.0 ref. |
| Yes | 535 (73.6) | 192 (26.4) | 1.11 (0.97 to 1.28) | 1.11 (0.97 to 1.28) | |
| 6 months | No | 962 (78.3) | 267 (21.7) | 1.0 ref. | 1.0 ref. |
| Yes | 576 (76.8) | 174 (23.2) | 1.05 (0.92 to 1.20) | 1.00 (0.87 to 1.15) | |
| 1 year | No | 1141 (78.2) | 318 (21.8) | 1.0 ref. | 1.0 ref. |
| Yes | 841 (74.4) | 290 (25.6) | 1.12 (1.02 to 1.24) | 1.11 (1.00 to 1.23) | |
| VAS-pain decrease over the median | |||||
| 3 months | No | 831 (75.3) | 273 (24.7) | 1.0 ref. | 1.0 ref. |
| Yes | 882 (76.8) | 266 (23.2) | 0.96 (0.87 to 1.06) | 1.06 (0.97 to 1.16) | |
| 6 months | No | 750 (77.9) | 213 (22.1) | 1.0 ref. | 1.0 ref. |
| Yes | 763 (78.3) | 212 (21.7) | 0.99 (0.89 to 1.10) | 1.08 (0.98 to 1.19) | |
| 1 year | No | 938 (75.9) | 298 (24.1) | 1.0 ref. | 1.0 ref. |
| Yes | 991 (77.5) | 288 (22.5) | 0.96 (0.87 to 1.05) | 1.05 (0.96 to 1.14) | |
| VAS-pain remission | |||||
| 3 months | No | 1055 (79.0) | 281 (21.0) | 1.0 ref. | 1.0 ref. |
| Yes | 710 (71.6) | 282 (28.4) | 1.25 (1.13 to 1.38) | 1.13 (1.02 to 1.26) | |
| 6 months | No | 892 (79.7) | 227 (20.3) | 1.0 ref. | 1.0 ref. |
| Yes | 663 (75.4) | 216 (24.6) | 1.14 (1.02 to 1.28) | 1.08 (0.96 to 1.22) | |
| 1 year | No | 1115 (79.0) | 297 (21.0) | 1.0 ref. | 1.0 ref. |
| Yes | 890 (73.6) | 319 (26.4) | 1.17 (1.07 to 1.28) | 1.10 (1.00 to 1.21) | |
| HAQ decrease over the median | |||||
| 3 months | No | 796 (76.9) | 239 (23.1) | 1.0 ref. | 1.0 ref. |
| Yes | 842 (74.8) | 283 (25.2) | 1.05 (0.96 to 1.16) | 1.11 (1.02 to 1.21) | |
| 6 months | No | 706 (79.0) | 188 (21.0) | 1.0 ref. | 1.0 ref. |
| Yes | 734 (76.6) | 224 (23.4) | 1.07 (0.96 to 1.18) | 1.10 (0.99 to 1.21) | |
| 1 year | No | 872 (78.6) | 237 (21.4) | 1.0 ref. | 1.0 ref. |
| Yes | 949 (74.6) | 323 (25.4) | 1.11 (1.02 to 1.20) | 1.15 (1.06 to 1.25) | |
Risk ratio crude: poisson regression estimates without adjustment. Risk ratio*: poisson regression estimates adjusted for age at the diagnosis, gender, alcohol assumption, pack-years of smoking, body mass index, and baseline outcome values. DAS28 disease activity in 29 joints, VAS visual analog scale, HAQ health assessment questionnaire